rad18

ID

ZDB-GENE-040426-745

Name

RAD18 E3 ubiquitin protein ligase

Symbol

rad18 Nomenclature History

Previous Names

zgc:55577

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable metal ion binding activity; single-stranded DNA binding activity; and ubiquitin protein ligase activity. Predicted to be involved in DNA damage tolerance and protein monoubiquitination. Predicted to act upstream of or within DNA repair. Predicted to be part of Rad6-Rad18 complex. Predicted to be active in nucleus. Orthologous to human RAD18 (RAD18 E3 ubiquitin protein ligase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rad18 Human Ortholog

No data available

Associated With rad18 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017907	Zinc finger, RING-type, conserved site
Domain	IPR001841	Zinc finger, RING-type
Domain	IPR003034	SAP domain
Domain	IPR006642	Rad18, zinc finger UBZ4-type
Family	IPR039577	E3 ubiquitin-protein ligase Rad18
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M3B0K8	InterPro	393
UniProtKB:Q803L3	InterPro	426
UniProtKB:A0AB32TQL4	InterPro	426
UniProtKB:A0AB32TS73	InterPro	392
UniProtKB:A0AC58JQN1	InterPro	425
UniProtKB:A0AC58JQP5	InterPro	392